New Regulator Identified In Allergic Diseases

Main Category: Allergy
Also Included In: Respiratory / Asthma;  Immune System / Vaccines
Article Date: 29 Mar 2012 1:00 PDT

email to a crony   printer accessible   opinions  

! rate article

Patient / Public:
Healthcare Prof:

Researchers have taken a vicious step in bargain how allergic reactions start after identifying a genetic signature for law of a pivotal defence hormone, interleukin (IL-13).

Scientists from Cincinnati Childrens Hospital Medical Center contend a anticipating opens a intensity for new molecular targets to provide allergic disease. They news in Mucosal Immunology that a sold microRNA, miR-375, is regulated by IL-13, and in turns regulates how IL-13 induces pro-allergic changes, quite in epithelial cells in a lung and esophagus.

The information support a purpose for miR-375 in asthma and in eosinophilic esophagitis (EoE), a severe, mostly unpleasant food allergy that renders children incompetent to eat a far-r...