New Treatment Directions Suggested By Alzheimer’s Protein Structure

<p>Main Category: Alzheimers / Dementia
Also Included In: Cholesterol
Article Date: 02 Jun 2012 0:00 PDT</p>

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The molecular structure of a protein concerned in Alzheimers illness and a startling find that it binds cholesterol could lead to new therapeutics for a disease, Vanderbilt University investigators news in a Jun 1 emanate of a biography Science.</p>

<p>Charles Sanders, Ph.D., highbrow of Biochemistry, and colleagues in a Center for Structural Biology dynamic a structure of partial of a amyloid predecessor protein (APP) a source of amyloid-beta, that is believed to trigger Alzheimers disease. Amyloid-beta clumps together into oligomers that kill neurons, causing insanity and memory loss. The amyloid-beta oligomers eventually form plaques in a mind one of a hallmarks of a disease.</p>

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